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Acrolein

 

Vinyl Chloride

Some anticancer drugs discussed above (press buttons for more information)
cyclophosphamide etoposide doxorubicin bleomycin methotrexate cytarabine
 
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References 

  1. Slatery ML, Samowitz W, Curtin K, Khe NH, Hoffman M, Caasn B, Neuhausen S. Associations among IRS-1, IRS-2, IGF-I, and IGFBP3 Genetic Polymorphisms Colorectal Cancer, Cancer Epidemiol Biomarkers Prev 2004; 13(7), July, 2004.

    1. Singh P, Rubin N Insulinlike growth factors and binding proteins in colon cancer.  Gastroenterology,1993; 105: 1218-1237.

    2. Werner H, Le Roith D. The insulin like growth factor I receptor signaling pathways are important for tumorigenesis and inhibition of apoptosis. Crit Rev Oncog 1997; 8: 71-92.

    3. Sandhu MS, Dunger DB, Giovannucci EL.  Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biological interactions and colorectal cancer. J. Natl Cancer Inst 2002; 94: 972-980.

  2. Borofsky ND, Vogelman JH, Krajcik RA, Orentreich N. Utility of insulin-like growth factor-1 as a biomarker in epidemiologic studies. Clinical Chemistry 48, No. 12, 2002.

    1. Yu H, Rohan R. Role of the insulin-like growth factor family in  cancer development and progression [Review] J Natl Cancer Inst 2000; 92: 1472-1489.

    2. Chan JM, Stampfer MJ, Giovannucci E, Gann PH, Ma J, Wilkinson, P. et al. Plasma insulin-like growth factor and prostate cancer risk; a prospective study. Science 1998: 279: 563-566.

    3. Kraaks R, Toniolo P, Akhmedkhanov A, Lukanova A, Biessy et al.  Serum C-peptide, insulin like growth factor (IGF-I), IGF-binding proteins, and colorectal cancer risk in women. J Natl Cancer Inst 2002; 92: 1592-1600.

    4. Langlois JA, Rosen CJ, Viser M, Hannan MT, Harris T, Wilson PWF, et al. Association between insulin-like growth factor 1 and bone mineral density in older women and men: the Framingham  Heart Study. J. Clin Endocrinol Metab 1998; 83:4257-4262.

    5. Aleman A, Verhaar HJJ De Haan EHF, De Vries WR, Sampson MM, Drent ML et al. Insulin-like growth factor 1 and cognitive function in healthy older men.J Clin Endorinol Metab 1999; 84: 471-475.

    6. Janssen JAMJL, Stolk RP, Pols HAP, Grobbee DE, Lamberts SWJ. Serum total IGF-I, free IGF-I, and IGFBP1 levels in an elderly population.  Relation to cardiovascular risk factors and disease.Arterioscler Throm Vasc Biol 1998; 18:277-282.

  3. Strickland PT,  Kensler TW, Genesis of Cancer B: "Environmental Factors" in Clinical Oncology, 4th Edition (Abeloff MD, Armirtage, JO, Niederhuber, JE, Kastan MB, McKenna, WG, eds), Elsevier Churchill-Livingstone, Philadelphia, 2008, pp. 125-138.
  4. Perry MC, Longo DL Chapter e13. Late Consequences of Cancer and its Treatment) in Harrison's Principles of Internal Medicine, 17th edition (Fauci AS, Braunwald E, Kasper DL, Hauser, SL, Longo DL, Jameson JL, Loscalzo J., eds) McGraw-Hill Medical, New York, 2008.
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