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Oncology General Principles

 

Lifetime Risks (of diagnosis and death) for Some Cancers and for Overall Disease3

 

Incidence and Mortality of the 10 Cancers most common in the U.S. for Malesd

Rank

Men

Incidencea

Mortalitya

1

Prostate

178

30

2

Lung

82

76

3

Colorectal

63

25

4

Bladder

38

8

5

Non-Hodgkin's lymphoma

24

10

6

Melanoma

23

4

7

Oral cavity/pharynxc

16

4

8

Kidney

17

6

9

Leukemiasb

16

10

10

Pancreas

13

12

a Rates per 100,000 (1998-2002, age adjusted using year 2000 U.S. census data with 5-year grouping

b All leukemia subtypes included: [Major subtypes include: ALL (acute lymphoblastic leukemia), AML (acute myelogenous leukemia), CLL (chronic lymphocytic leukemia), and CML (chronic myelogenous leukemia]

c Includes both larynx and oropharynx

d SEER database (NCI SEER program; Ries LAD et al (eds): SEER Cancer Statistics Review, 1975-2002, NCI, 2005 and reference 1.

 

Incidence and Mortality of the 10 Cancers most common in the U.S. for Femalesd

Rank

Women

Incidencea

Mortalitya

1

Breast

137

26

2

Lung

51

41

3

Colorectal

47

17

4

Uterus

33

7

5

Ovary

14

9

6

Non-Hodgkin's Lymphoma

16

7

7

Melanoma

15

2

8

Thyroid

11

0.5

9

Pancreas

10

9

10

Leukemiab

10

6

a Rates per 100,000 (1998-2002, age adjusted using year 2000 U.S. census data with 5-year grouping

b All leukemia subtypes included: [Major subtypes include: ALL (acute lymphoblastic leukemia), AML (acute myelogenous leukemia), CLL (chronic lymphocytic leukemia), and CML (chronic myelogenous leukemia]

c Uterus classification is inclusive of both cervix and corpus luteri

d SEER database (NCI SEER program; Ries LAD et al (eds): SEER Cancer Statistics Review, 1975-2002, NCI, 2005 and reference 1.

Annual Age-adjusted Cancer Death Rates Among Men (Selected Cancers)5

These rates are age-adjusted to the 2000 US standard population. The information is obtained from the US Mortality Public Use Data Tapes, 1960-2003, US Mortality Volumes, 1930-1959, National Center for Health Statistics, Centers for Disease Control and Prevention, 2006.

 

Annual Age-adjusted Cancer Death Rates Among Females (Selected Cancers)5

  • Rates are age-adjusted to the 2000 US standard population with the following notations:

    • † the uterus classification includes uterine cervix and uterine corpus.

    • The information is obtained from the US Mortality Public Use Data Tapes, 1960-2003, US Mortality Volumes, 1930-1959, National Center for Health Statistics, Centers for Disease Control and Prevention, 2006.

 

 

SEER Incidence: All Cancer Combined by Race and Sex2,4

  • Incidence rates are derived from SEER 17 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, and New Jersey) and these rates are age-adjusted in accordance with the 2000 US Census using 19 age groups.

 

5-Year Survival Rates Comparing White and Black Patients, both Sexes, based on SEER data collected from 1996-20042,4

  • Case data were obtained from SEER 17 areas: (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, and New Jersey). 
  • California with the above California-state exclusions, Kentucky, Louisiana, and New Jersey contributed cases for this analysis for diagnostic years 2000-2004, whereas the remaining 13 SEER areas contributed cases for the entire 1996-2004 timeframe.

 

SEER Cancer Incidence and US Death Rates based on data compiled between 2001-2005 by Cancer Site and Race2,4

Incidence (red)

Cancer Site

Mortality (blue)

  • Information for this table was obtained from SEER 17 areas: (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, and New Jersey) along with U.S. Mortality Files, National Center for Health Statistics, Centers for Disease Control (CDC) and Prevention. 
  • Rates are expressed as per 100,000 and are age-adjusted to the 2000 US Std. Population, using 19 age groups [Census P25-1003].
  • Rates for American Indian/Alaska Native were based on the CHSDA (Contract Health Service Deliver Area) counties. 
  • Hispanic is noted not to be mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives.  The data for Hispanics were based on NHIA and excluded cases from the Alaska Native Registry and Kentucky. 
  • Mortality data for Hispanics excluded cases from Minnesota, New Hampshire, and North Dakota.

 

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References 
  1. Rugo, H.S., "Cancer" in 2008 Current Medical Diagnosis & Treatment (McPhee, S.J. and Papadakis, M.A., eds; Tierney, L.M. Jr, senior editor) McGraw-Hill Lange, 2008, New York 47th edition, pp. 1387-1390.
  2. SEER (Surveillance Epidemiology and End Results), 2008
  3. Information from SEER Cancer Statistics Review and reference 1.
  4. SEER graphs (Surveillance Epidemiology and End Results)
  5. Jemal, A, Siegel, R, Ward, E, Murray T, Xu, J, Thun MJ Cancer Statistics 2007, CA Cancer J. Clin 2007; 43-66. (current as of May 17, 2008); online version: http://caonline.amcancersoc.org/cgi/content/full/57/1/43
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